Bicyclol (Shuang Huan Chun tablets) (50mg *18 tablets) Chronic viral and non-viral liver disease with elevated serum aminotransferase abnormalities 双环醇片/Bicyclol
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Functions and Indications:
Bicyclol is exclusively produced by Beijing Union Pharmaceutical Factory with creation led by Academician Liu Gengtao from Institute of Materia Medica Chinese Academy of Medical Sciences, enjoys a 12-year protection period of new drugs from market launch in November 2001, and is a Class 1.1 new chemical drug with international proprietary intellectual property rights available on the market.
Phase Ⅰ~Ⅳ clinical trials and extensive application after market launch prove that, Bicyclol is suitable for the treatment of chronic viral and non-viral liver disease with elevated serum aminotransferase abnormalities, and is excellent in safety. This drug is recommended for liver protection and anti-inflammatory medication by Chinese Medical Association in Guidelines for Management of Alcoholic Fatty Liver Disease, Guidelines for Management of Non-alcoholic Fatty Liver Disease, The Guideline of Prevention and Treatment for Chronic Hepatitis B, Expert Consensus On Hepatic Inflammation and Its Prevention and other professional guidelines and consensus; included in National Basic Medical Insurance, Work-Related Injury Insurance and Maternity Insurance Drug List, Army Reasonable Medical Drug List and several provincial NCMS lists. Over 350 academic papers on basic and clinical research with Bicyclol as the theme (nearly 40 SCI indexed journals) have been published at home and abroad.
Bicyclol is known as a successful example of "Created in China" in chemical and pharmaceutical industry: In 2001, winning the outstanding scientific achievement award of "Ninth Five-Year Plan" national key scientific and technological projects; In 2002, included in high-tech industry development projects of National Development Planning Commission and Beijing high-tech achievement conversion projects, recognized as one of national key new products; In 2003, included in Beijing Spark Program; In 2004, included in Ministry of Science and Technology the Action Plan of Revitalizing Trade through Science and Technology; In 2005, winning the first prize of Beijing Science and Technology Award; In 2007, awarded the 2nd Prize of National Science and Technology Progress Award. Currently, Beijing Union Pharmaceutical Factory has 10 patents for bicyclol invention, and a number of research topics on new mechanisms, new dosage forms, and new applications.
Since market launch, Bicyclol has presented excellent liver health care achievements, creating significant social and economic benefits, and rated as Beijing Famous Brand. With quality advantage, Bicyclol has completed registration and launched into markets in Ukraine, Kazakhstan, Uzbekistan, Tajikistan, Kyrgyzstan, Georgia and Moldova; and has obtained GMP certificate from Ukraine, a member state of Pharmaceutical Inspection Convention (PIC/S) in 2014, providing valuable experiences for the internationalization of innovative medicines.
Dosage and Administration:
Oral, adult dosage once 25mg , when necessary, can be increased to 50mg , 3 times a day, taking at least 6 months or according to the doctor's advice, should gradually reduce.
Adverse effects :
After taking this product, the possible adverse reactions of individual patients are mild or moderate, and generally do not need to stop taking medicine, or a brief withdrawal, or symptomatic treatment can relieve.
In 2200 patients aged 12 to 65 years old with the Bicyclol Tablets IV clinical study, there is no serious adverse reaction, the researchers report 30 cases with this product are likely related adverse events or may be related to the occasional (incidence rate <0.5%) skin rash, dizziness, abdominal distension, nausea, very few (incidence rate <0.1%) headache, serum aminotransferase levels, sleep disorders, stomach discomfort, thrombocytopenia, a transient increase of serum creatinine, blood sugar alopecia.
1. Patients with hepatic decompensation include elevated bilirubin, hypoalbuminemia, cirrhosis, ascites, variceal bleeding, hepatic encephalopathy, and hepatorenal syndrome use the medicine cautiously.
2. Pregnant woman don't use it.
Storage : Store (keep) in a cool and dry place,protect from light (heat).
Product Name :Bicyclol (Shuang Huan Chun tablets)
Packing: 50mg *18 tablets/one box
Manufacturer : BeiJing XieHe Pharmaceutical Co. Ltd